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The mechanism of action for Endostatin remains unclear, although reports from the 91st AACR Meeting in April showed that recombinant human endostatin bound to a number of tropomyosin cDNAs in a library screen [].

In preclinical studies, repeated administration of Endostatin consistently shrank primary tumors and did not produce any drug resistance.

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Types of cancers which respond to Endostatin include lung, skin, vascular and fibrosarcomas. Toxicology studies in cynomolgus monkeys showed that bolus injections of Federal Register, Internacional, a swimming event. The event is scheduled to take place on Sunday, September 2, Approximately 85 swimmers are anticipated to participate in the swimming event, and there are not expected to be The first Seminario Internacional Sobre la Educacion Bilingue International Seminar on Bilingual Educationunder the aegis of the National Association for Bilingual Education and the Mexican secretary for public education, brought together professionals from Canada, the United States, and Mexico in Oaxtepec, Mexico in November to share… NASA Astrophysics Data System ADS Chasse, Dominique L'effet Josephson est generalement presente comme le resultat de l'effet tunnel coherent de paires de Cooper a travers une jonction tunnel entre deux supraconducteurs, mais il est possible de l'expliquer dans un contexte plus general.

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Puisque cette description se generalise de facon naturelle a des brisures de symetries continues non-abeliennes, l'equivalent de l'effet Josephson devrait donc exister pour des types d'ordre a longue portee differents de la supraconductivite.

Le cas de deux ferroaimants itinerants brisure de symetrie 0 3 couples a travers une jonction tunnel a deja ete traite dans la litterature Afin de mettre en evidence la generalite du phenomene et dans le but de faire des predictions a partir d'un modele realiste, nous etudions le cas d'une jonction tunnel entre deux antiferroaimants itinerants.

La fonction sinus caracteristique du courant Josephson standard est donc remplacee.

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Nous montrons que, d'un point de vue microscopique, ce phenomene resulte de l'effet tunnel coherent de paires particule-trou de spin 1 et de vecteur d'onde net egal au vecteur d'onde antiferromagnetique Q. We investigated the hypothesis that vesical contraction is maintained by positive feedback through continuous flow of urine through the urethra, and that the cessation of urine flow aborts detrusor contraction.

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Normal saline was infused into the urinary bladders of 17 healthy volunteers age On urge, which occurred at a mean volume of The test was repeated after anesthetizing the urethra with xylocaine gel or, on another occasion, after applying a bland gel.

On micturition, the urine was evacuated as a continuous stream without straining; no residual fluid was collected. After urethral anesthetization, the fluid came out of the urethra in multiple intermittent spurts and only with excessive straining.

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There was a large amount of residual fluid Detrusor contraction during micturition is suggested to be maintained by positive urethrovesical feedback elicited by the continued passage of urine through the urethra. This feedback seems to be effected through the urethrovesical reflex, which produces vesical contraction on stimulation of the urethral stretch receptors.

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Abortion of this reflex by urethral anesthetization resulted in failure of detrusor contraction and excessive straining was needed to achieve bladder evacuation in multiple spurts. The urethrovesical reflex is thus assumed to constitute a second micturition reflex responsible for the continuation of detrusor contraction and urination.